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Cardiac Intervention

Transcatheter Mitral Valve Replacement (TMVR)

A catheter-based, non-surgical technique to replace a severely diseased mitral valve, offered for patients unfit for open mitral valve surgery.

Procedure Catheter-based intervention
Hospital Stay Depends on recovery
Recovery Generally faster
Suitability After specialist evaluation

Understanding Transcatheter Mitral Valve Replacement (TMVR)

What is Transcatheter Mitral Valve Replacement?

The mitral valve controls blood flow between the left atrium and the left ventricle. When this valve becomes severely diseased — either narrowed (mitral stenosis) or leaking (severe mitral regurgitation) — the heart has to work far harder, leading to breathlessness, fatigue, palpitations and fluid accumulation in the lungs. Transcatheter Mitral Valve Replacement (TMVR) is a minimally invasive alternative to open mitral valve surgery, in which a new valve is delivered through a catheter and implanted within or around the diseased native mitral valve, or within a previously placed surgical valve or ring.

Who is a Candidate for TMVR?

  • Patients with severe mitral valve disease who are at high or prohibitive risk for open-heart surgery
  • Patients with a degenerated surgical mitral bioprosthesis (valve-in-valve TMVR)
  • Patients with a failing surgical annuloplasty ring (valve-in-ring TMVR)
  • Patients with severe mitral annular calcification not suitable for conventional surgery

How is TMVR Performed?

Detailed pre-procedural imaging with transoesophageal echocardiography and CT is performed to assess the mitral anatomy and plan the ideal access route, which may be transseptal (through the femoral vein and across the atrial septum) or transapical. The replacement valve is then precisely positioned and deployed within the native mitral valve under live imaging guidance, immediately restoring competent valve function.

Benefits of TMVR

  • Avoids the risks of open-heart mitral valve surgery in high-risk patients
  • Immediate improvement in valve function and symptoms
  • Shorter recovery time compared to surgical mitral valve replacement
  • A valuable option when repeat mitral surgery carries very high risk

Recovery After TMVR

Most patients notice a marked improvement in breathlessness and exercise tolerance within days of the procedure. Hospital stay is usually a few days, followed by structured outpatient follow-up with echocardiography and medication review.

Why Choose Dr. Prashant Dwivedi for TMVR in Jaipur?

Dr. Prashant Dwivedi is among the select group of cardiologists in India specially trained in TMVR at Mount Sinai Hospital, New York. His structural heart team in Jaipur offers meticulous pre-procedural imaging and individualised planning for every mitral valve case.

Treatment suitability is confirmed only after clinical examination, cardiac imaging and detailed assessment by the specialist.

How the intervention is planned

Every procedure is planned according to the patient’s heart anatomy, symptoms and overall medical condition.

01

Detailed Evaluation

Transoesophageal echocardiography and CT define the mitral anatomy and guide device sizing.

02

Heart Team Planning

The transseptal or transapical access route and valve strategy are carefully selected.

03

Valve Delivery and Deployment

The replacement valve is advanced on a catheter and precisely deployed within the native or previously implanted mitral valve.

04

Monitoring and Recovery

Heart function is monitored closely, with most patients discharged within a few days.

05

Long-Term Follow-up

Regular echocardiography and medication review confirm sustained valve function.

Dr. Prashant Dwivedi

Dr. Prashant Dwivedi

Interventional and Structural Heart Cardiologist

Dr. Prashant Dwivedi has extensive experience in structural heart interventions, combining detailed imaging, careful procedural planning, international training and personalised patient care.

Structural Heart Expertise Advanced Cardiac Imaging Patient-Centred Care
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Questions about Transcatheter Mitral Valve Replacement (TMVR)

General information to help patients understand the intervention and treatment process.

TMVR is used to treat severe mitral valve disease, including severe mitral regurgitation or stenosis, especially in patients with a failed surgical mitral valve or ring, or those at high risk for open mitral surgery.

No. TMVR replaces the mitral valve entirely using a catheter-delivered prosthetic valve, whereas MitraClip repairs the patient's own valve by clipping the leaflets together. Your cardiologist will recommend the most suitable option after detailed imaging.

Access route — transseptal (through a vein) or transapical — is decided based on detailed CT and echocardiographic assessment of the heart and mitral valve anatomy to ensure the safest and most effective valve placement.

Most patients stay in hospital for a few days after TMVR and notice significant improvement in breathlessness and energy levels within the first week, followed by structured outpatient follow-up.

Get expert guidance for your heart condition

Schedule a consultation with Dr. Prashant Dwivedi for accurate evaluation, transparent advice and advanced cardiac treatment planning.

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