Transcatheter Mitral Valve Replacement (TMVR) TMVR

A catheter-based technique to replace a severely diseased mitral valve, offered for patients unfit for open mitral valve surgery.

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Procedure Type Minimally invasive

Hospital Stay Usually 24–48 hours

Recovery Generally faster

Suitability After cardiac evaluation

Treatment Overview

TMVR Treatment

TMVR is a structural heart treatment used to replace a severely diseased mitral valve using catheter-based technology, avoiding open-heart surgery in carefully selected patients with severe mitral stenosis or regurgitation.

Patient suitability is determined after detailed clinical examination, echocardiography and evaluation of the defect’s size, position and anatomy.

Conditions Treated

Conditions treated with TMVR

Severe MR Severe Mitral Regurgitation

Significant leakage of the mitral valve causing breathlessness, fatigue and fluid accumulation in the lungs.

Mitral Stenosis Severe Mitral Valve Stenosis

Narrowing of the mitral valve restricting blood flow into the left ventricle.

Valve-in-Valve Degenerated Surgical Mitral Valve

A previously implanted surgical mitral bioprosthesis that has failed and requires valve-in-valve TMVR.

Valve-in-Ring Failing Surgical Annuloplasty Ring

A previously placed mitral repair ring that is no longer functioning adequately, treatable with valve-in-ring TMVR.

Procedure

How the TMVR procedure is performed

Detailed pre-procedural imaging with transoesophageal echocardiography and CT is performed to assess the mitral anatomy and plan the access route, which may be transseptal (through the femoral vein) or transapical. The replacement valve is then precisely positioned and deployed within the native mitral valve, a degenerated surgical bioprosthesis, or a failing surgical ring, restoring competent valve function immediately.

The procedure is performed in a specialised cardiac catheterisation laboratory. Continuous imaging allows accurate positioning of the device and assessment of the result before completion.

Key Benefits

Benefits of TMVR

Avoids the risks of open-heart mitral valve surgery in high-risk patients
Immediate improvement in valve function and symptoms
Shorter recovery time compared to surgical mitral valve replacement
A valuable option when repeat mitral surgery carries very high risk
Treats native valve disease as well as failed surgical valves and rings

Recovery

Recovery after the procedure

Most patients notice a marked improvement in breathlessness and exercise tolerance within days of the procedure. Hospital stay is usually a few days, followed by structured outpatient follow-up with echocardiography and medication review.

Medication instructions and follow-up schedules should be followed carefully. Contact the treating doctor immediately in case of unusual pain, bleeding, swelling, fever or breathing difficulty.

Treatment Journey

What happens during the procedure?

Each treatment is planned according to the patient’s heart anatomy, medical condition and clinical requirements.

Detailed Imaging Work-up

Transoesophageal echocardiography and CT define the mitral anatomy and guide device sizing and access planning.

Access Route Selection

A transseptal (through the vein) or transapical access route is chosen based on individual anatomy.

Valve Delivery

The replacement valve is advanced on a catheter to the mitral position under live imaging guidance.

Valve Deployment

The valve is precisely positioned and deployed within the native or previously implanted mitral valve.

Confirmation and Recovery

Echocardiography confirms correct valve function before the procedure is completed.

Your Heart Specialist

Dr. Prashant Dwivedi

Interventional and Structural Heart Cardiologist

Dr. Prashant Dwivedi is among the select group of cardiologists in India specially trained in TMVR at Mount Sinai Hospital, New York, offering meticulous pre-procedural imaging and individualised planning for every mitral valve case in Jaipur.

Structural Heart Expertise Advanced Catheter Procedures Patient-Centred Care

Frequently Asked Questions

Questions about TMVR treatment

General information to help patients understand the procedure. Individual advice may differ according to medical condition.

TMVR replaces the mitral valve entirely using a catheter-delivered prosthetic valve, whereas MitraClip repairs the patient's own valve by clipping the leaflets together.

Yes, TMVR can be used as valve-in-valve therapy for a degenerated surgical mitral bioprosthesis, or valve-in-ring therapy for a failing surgical annuloplasty ring.

Detailed transoesophageal echocardiography and CT imaging are performed to assess the mitral valve anatomy and plan the safest access route and valve size.

Many patients notice a marked improvement in breathlessness and exercise tolerance within days of the procedure.

Get expert guidance for your heart condition

Schedule an appointment with Dr. Prashant Dwivedi for accurate evaluation, personalised advice and advanced cardiac treatment planning.